Ayurveda says that each substance within the universe has the potential to be a medication supplied it’s used judiciously by the doctor and affected person. Within the Charaka Samhita, it’s stated:
“Anenopadeshen Na Anaushadhibhootam Jagati Kincit dravyam upalabhyate
Taam Taam Yuktimartham Ca Tam Tamaabhipretya”
Which implies, “Substances discovered within the universe are categorized primarily based on the supply of origin. Substances from animals are referred to as Jangama (milk, meat, urine, blood, serum), substances from plant are referred to as Audbhida (fruits, leaves, root, sap), and substances from minerals and metals are referred to as Paarthiwa or Khanija (gold, silver, copper, iron). The realm of Ayurveda that offers with mineral origin substances is “Rasa Shastra”. Rasa Shastra actually means “Science of Mercury”. It offers with the examine of minerals and metals that don’t restrict its makes use of to alchemy alone but additionally to therapeutic makes use of.
Rasa shastra was developed by Sage Naagaarjuna, the Father of Rasa shastra” across the eighth century. He stated, “Siddhe Rase Karishyaami Nirdaridryamidam jagat”, which suggests “I’ll eradicate poverty from this world by experimenting with mercury.” Though the examine of Rasa shastra means examine of mercury and the methods to course of it, within the current day, it’s the examine of all metallic substances and minerals. Rasa-oushadi (medicines from metals and minerals) is a category of medication prescribed for a lot of illnesses by Rasa-vaidyas.
Rasa-oushadi’s are categorized into 4 classes- Rasa, Dhaatu, Visha and Ratna. Rasa offers with the medication that possess Rasayana impact (adaptogenic impact). Rasayanas enhance Ojas, cures illnesses and delays ageing. Dhaatu offers with offering power to the physique. Ratna incorporates the minerals that possess gem high quality. Visha because the title suggests are these which are extremely toxic crops.
Bhasmas in Rasa Shastra are the ayurvedic metallic/mineral preparation which are handled with herbs to deal with many power illnesses. They’re biologically produced nanoparticles which are ready by two well-known methods- Putapaka technique and the Kupipakwa technique.
Within the Putapaka technique, the metals are subjected to a few steps- Shodhana, Bhavana and Marana). Metals are become coarse powder and heated to purple sizzling temperatures following which they’re quenched in a selected liquid. This contains of the purification process- Shodhana. The purified metallic is blended with particular medication which are incinerated and levigated in liquid. This course of is named moist grinding- Bhavana. The levigated mass are become small pellets which are positioned in earthern crucibles, sealed by mud smeared garments and heated in an electrical muffle furnace (Puta). This course of is named Putapaka. The crucibles are heated for a selected time interval, cooled and the incinerated powder is extracted.
Within the Kupipakwa technique, the metals are subjected to 4 steps. After Shodhana (as described above), the metals are amalgamated with Mercury and blended with sulphur. This combination is triturated till it turns black, lusterless and a clean powder. This process is termed Kajjali. The Kajjali is floor in liquid media for a while and allowed to dry in a glass bottle (Kachkupi). The bottle is wrapped in a number of layers of mud smeared fabric and heated on a sand tub. The bottle is cooled and damaged to extract the Bhasma that stays on the backside of the bottle. The extracted Bhasma is floor into powder.
What’s fascinating is the science concerned throughout this complete strategy of Bhasma-making. This solely proves increasingly more the science in Ayurveda. The repeated heating and cooling processes disrupts the stress within the metals making them brittle and comfortable. This additionally leads to discount in particle dimension. The purified metallic is floor in moist state as a result of moist grinding eliminates mud and likewise finer dimension is healthier achieved on this course of. Lastly, when metals are incinerated, compounds are shaped on the metallic floor which are extra beneficial to the physique.
After the Bhasma is ready, it undergoes a collection of assessments to verify whether it is correctly incinerated or not. These embody observing the lustre (Chandrika) (Bhasma have to be lustreless- nischandrika), the lightness and fineness, style and extra.
Bhasmas are close to to the scale of nanoparticles. The scale may be diminished through the strategy of trituration and Bhavana. Bhasma dimension ranges from 1-2 microns. Bhasmas of various metallic cocktails are used for numerous illnesses akin to respiratory tract infections, headache, fever, blood strain, diarrhoea, jaundice, anaemia, cancers, calcium deficiency, swelling in joints, and extra.
Bhasmas are simply absorbed into the physique, they cleanse the kidney (used as a diuretic), liver (helps in cirrhosis), stronger bones and tooth, maintains a rhythmic heartbeat, protects the physique from free radical injury.
Regardless of the above makes use of, the rumoured presence of heavy metals didn’t permit its utilization. The dearth of reproducibility can be hindering its common acceptance. Dr Kattesh Katti, nanotech scientist on the College of Missouri has developed a “Nano-ayurvedic drugs” that very lately was authorised by the US Patents and Commerce Marks Workplace. This growth has opened avenues for greener options within the biomedical subject.
Within the subject of most cancers therapeutics, focused drug supply is essential and broadly studied. This helps to scale back the frequency of the dosages and there’s discount within the fluctuating drug concentrations within the physique. Nanoparticles are additionally nice drug supply brokers and enhance drug stability and management the discharge of the drug into the blood/serum. Moreover, the drug stays secure till it reaches the goal organ. In accordance with Dr Katti, phytochemicals from many crops are a reservoir of electrons due to their antioxidant properties they usually can be utilized to fabricate inexperienced nanoparticles.
Dr Katti’s crew has labored for over 20 years to develop universally acceptable ayurvedic formulations with the assistance of inexperienced nanotechnology. They laid concentrate on gold nanoparticles that can be utilized together with phytochemicals from herbs akin to mango, grape, turmeric, cinnamon, clove and many others. These crops are electron-rich and the interplay between gold particles with electrons from the above talked about plant-derived phytochemicals produces well-defined gold nanoparticles. It’s fascinating to notice that these Gold nanoparticles are much like Swarna Bhasma. Research have proven that its’ options impede international acceptance.
This Nano-ayurvedic drugs gold nanoparticle drug was examined on in-vitro breast tumour cells and was additionally administered to metastatic breast most cancers sufferers in a pilot human medical trial performed based on the rules set by the Ministry of AYUSH. The examine revealed that the drug demonstrated wonderful efficacy within the sufferers with extremely diminished hostile results as in comparison with customary chemotherapy. Moreover, there was minimal systemic toxicity.
Rasa shastra is an age previous science much like right now’s nanotechnology. When Ayurveda meets fashionable science and fashionable drugs, wonders are certain to occur. If the worldwide neighborhood is increasingly more accepting of those wonders, it may give rise to a wholesome and blissful planet.
Concerning the Writer
Ms Varsha Venkataraman
Varsha Venkataraman is a graduate in Utilized Microbiology and Most cancers Research. At present she is the Senior Researcher for the Centre for Mushy Energy with an avid curiosity in Ayurveda and desires to concentrate on the integrative method of Ayurveda and fashionable drugs within the therapy of most cancers.